1279034-23-9
Chemical Structure
Quinaprilat-d5
- CAS No.: 1279034-23-9
- Formula:C23H21D5N2O5
- Molecular Weight:415.49
IUPAC Name: (S)-2-(((S)-1-carboxy-3-(phenyl-d5)propyl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
InChIKey: FLSLEGPOVLMJMN-KKQRNKNXSA-N
SMILES: C([C@@H](N[C@@H](CCC1=C(C(=C(C(=C1[2H])[2H])[2H])[2H])[2H])C(O)=O)C)(=O)N2[C@H](C(O)=O)CC=3C(C2)=CC=CC3
Biological Activity: Quinaprilat-d5 is a deuterium-labeled Quinaprilat (HY-127026). Quinaprilat is a nonsulfhydryl ACE inhibitor, the active diacid metabolite of Quinapril. Quinaprilat specifically blocks the conversion of angiotensin I to the vasoconstrictor angiotensin II and inhibits bradykinin degradation. Quinaprilat primarily acts as a vasodilator, decreasing total peripheral and renal vascular resistance[1].
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Quinaprilat-d5 | Quinaprilat-d5 is a deuterium-labeled Quinaprilat (HY-127026). Quinaprilat is a nonsulfhydryl ACE inhibitor, the active diacid metabolite of Quinapril. Quinaprilat specifically blocks the conversion of angiotensin I to the vasoconstrictor angiotensin II and inhibits bradykinin degradation. Quinaprilat primarily acts as a vasodilator, decreasing total peripheral and renal vascular resistance. | |||||||||||||||||||||
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Quinaprilat (Standard) | ≥98% | Quinaprilat (Standard) is the analytical standard of Quinaprilat (HY-127026) . This product is intended for research and analytical applications. Quinaprilat is an orally active non-mercapto Angiotensin Converting Enzyme (ACE) inhibitor, the active metabolite of Quinapril. Quinaprilat specifically blocks the conversion of angiotensin I to the vasoconstrictor angiotensin II and inhibits the degradation of bradykinin. Quinaprilat acts as anti-hypertensive agent and vasodilator. | ||||||||||||||||||||
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Quinaprilat | 96.79% | Quinaprilat is an orally active non-mercapto Angiotensin Converting Enzyme (ACE) inhibitor, the active metabolite of Quinapril. Quinaprilat specifically blocks the conversion of angiotensin I to the vasoconstrictor angiotensin II and inhibits the degradation of bradykinin. Quinaprilat acts as anti-hypertensive agent and vasodilator. | ||||||||||||||||||||
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