129437-45-2
Chemical Structure
Tumour-associated MUC1 epitope
- CAS No.: 129437-45-2
- Formula:C80H127N25O28
- Molecular Weight:1887.02
InChIKey: PWNGANMXYYXQIH-CQZRLPCDSA-N
SMILES: O=C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)CC2=CN=CN2)=O)=O)[C@H]3N(CCC3)C([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CO)NC(CNC([C@H]4N(CCC4)C([C@H](C)NC([C@H]5N(CCC5)C([C@H](CCCNC(N)=N)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@@H]6CCCN6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.)
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Tumour-associated MUC1 epitope | Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.) | |||||||||||||||||||||
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Keywords
