1308808-22-1
1308808-22-1
Chemical Structure
(Z)-Norendoxifen
- CAS No.: 1308808-22-1
- Formula:C24H25NO2
- Molecular Weight:359.46
InChIKey: YCQBLTPGQSYLHD-VHXPQNKSSA-N
SMILES: CC/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)O)/C3=CC=C(C=C3)OCCN
Biological Activity: (Z)-Norendoxifen is an aromatase inhibitor and estrogen receptor modulator. The IC50 value of (Z)-Norendoxifen against aromatase is 102 nM. The EC50 values of (Z)-Norendoxifen for ER-α and ER-β are 27.0 nM and 35.2 nM, respectively. (Z)-Norendoxifen can be used in breast cancer research[1].
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(Z)-Norendoxifen | (Z)-Norendoxifen is an aromatase inhibitor and estrogen receptor modulator. The IC50 value of (Z)-Norendoxifen against aromatase is 102 nM. The EC50 values of (Z)-Norendoxifen for ER-α and ER-β are 27.0 nM and 35.2 nM, respectively. (Z)-Norendoxifen can be used in breast cancer research. | |||||||||||||||||||||
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References
Keywords
