1309925-39-0
1309925-39-0
Chemical Structure
Tubulin inhibitor 8
- CAS 番号: 1309925-39-0
- Formula:C21H14N2O3
- Molecular Weight:342.35
IUPAC Name: 10-(4-methoxybenzoyl)-10H-phenoxazine-3-carbonitrile
InChIKey: JNDAHXOWDRYLBK-UHFFFAOYSA-N
SMILES: N#CC1=CC=C2N(C(C3=CC=C(OC)C=C3)=O)C4=C(C=CC=C4)OC2=C1
Biological Activity: Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM[1].
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Tubulin inhibitor 8 | Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM. | |||||||||||||||||||||
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References
Keywords
