1329835-60-0
1329835-60-0
Chemical Structure
Mexiletine-d6 hydrochloride
Synonym(s): KOE-1173-d6 hydrochloride
- CAS No.: 1329835-60-0
- Formula:C11H12D6ClNO
- Molecular Weight:221.76
IUPAC Name: 1-(2,6-dimethylphenoxy)propan-1,1,2,3,3,3-d6-2-amine hydrochloride
InChIKey: NFEIBWMZVIVJLQ-SJPQGYSLSA-N
SMILES: CC1=CC=CC(C)=C1OC([2H])([2H])C(N)([2H])C([2H])([2H])[2H].[H]Cl
Biological Activity: Mexiletine-d6 (hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1].
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Mexiletine-d6 hydrochloride | 99.79% | Mexiletine-d6 (hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker. | ||||||||||||||||||||
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Mexiletine hydrochloride (Standard) | ≥98% | Mexiletine (hydrochloride) (Standard) is the analytical standard of Mexiletine (hydrochloride). This product is intended for research and analytical applications. Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research. | ||||||||||||||||||||
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Mexiletine-d3 hydrochloride | Mexiletine-d3 (hydrochloride) is deuterium labeled Mexiletine (hydrochloride). Mexiletine hydrochloride (KOE-1173 hydrochloride), a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker. | |||||||||||||||||||||
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Mexiletine hydrochloride | 99.88% | Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research. | ||||||||||||||||||||
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References
