1335032-28-4
1335032-28-4
Chemical Structure
Sigma-1 receptor antagonist 6
- CAS No.: 1335032-28-4
- Formula:C32H34N6
- Molecular Weight:502.65
InChIKey: DQEUKKDHXQONBX-UHFFFAOYSA-N
SMILES: C#CCN(C)C1=NC(NCCCC2CCN(CC3=CC=CC=C3)CC2)=C(C#N)C(C4=CC=CC=C4)=C1C#N
Biological Activity: Sigma-1 receptor antagonist 6 (Compound 12) is an antagonist of the Sigma-1 receptor (σ1R). Sigma-1 receptor antagonist 6 exerts a robust antiallodynic effect by antagonizing σ1R. Sigma-1 receptor antagonist 6 can be used in neuropathic pain animal models to alleviate mechanical allodynia induced by paclitaxel (HY-B0015)[1].
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Sigma-1 receptor antagonist 6 | Sigma-1 receptor antagonist 6 (Compound 12) is an antagonist of the Sigma-1 receptor (σ1R). Sigma-1 receptor antagonist 6 exerts a robust antiallodynic effect by antagonizing σ1R. Sigma-1 receptor antagonist 6 can be used in neuropathic pain animal models to alleviate mechanical allodynia induced by paclitaxel (HY-B0015). | |||||||||||||||||||||
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References
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