1346013-80-6
1346013-80-6
Chemical Structure
UE2343
- CAS No.: 1346013-80-6
- Formula:C19H19N5O2S
- Molecular Weight:381.45
IUPAC Name: (5-(1H-pyrazol-4-yl)thiophen-3-yl)((1R,3r,5S)-3-hydroxy-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-8-yl)methanone
InChIKey: MMZFGTAMARVHAF-QWHZDKJVSA-N
SMILES: O=C(C1=CSC(C2=CNN=C2)=C1)N3[C@]4([H])C[C@@](C[C@@]3([H])CC4)(C5=NC=CC=N5)O
Biological Activity: UE2343 is an orally available, brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor. UE2343 is being investigated for the treatment of Alzheimer's disease[1].
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UE2343 | UE2343 is an orally available, brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor. UE2343 is being investigated for the treatment of Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
