13551-87-6
13551-87-6
Chemical Structure
Misonidazole
Synonym(s): Ro 7-0582; SR 1354
- CAS No.: 13551-87-6
- Formula:C7H11N3O4
- Molecular Weight:201.18
IUPAC Name: 1-methoxy-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol
InChIKey: OBBCSXFCDPPXOL-UHFFFAOYSA-N
SMILES: COCC(O)CN1C([N+]([O-])=O)=NC=C1
Biological Activity: Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer[1]. Misonidazole also has antimicrobial effects[2].
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Misonidazole | Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer. Misonidazole also has antimicrobial effects. | |||||||||||||||||||||
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References
- [1]. Bibo Li, et al. Preparation, Characterization, and In Vitro pH-sensitivity Evaluation of Superparamagnetic Iron Oxide Nanoparticle- Misonidazole pH-sensitive Liposomes. Curr Drug Deliv. 2019;16(3):254-267. [Content Brief]
- [2]. R C Knight, et al. Mechanism of action of nitroimidazole antimicrobial and antitumour radiosensitizing drugs. Effects of reduced misonidazole on DNA. Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Oct;36(4):367-77. [Content Brief]
Keywords
