1356354-25-0
Chemical Structure
Nafcillin-d5 sodium
- CAS No.: 1356354-25-0
- Formula:C21H16D5N2NaO5S
- Molecular Weight:441.49
IUPAC Name: sodium (2S,5R,6R)-6-(2-(ethoxy-d5)-1-naphthamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
InChIKey: AYAPZOUDXCDGIF-LYVUTDJTSA-M
SMILES: O=C([C@@H]1N2[C@@](SC1(C)C)([H])[C@@H](C2=O)NC(C3=C(OC([2H])([2H])C([2H])([2H])[2H])C=CC4=C3C=CC=C4)=O)O[Na]
Biological Activity: Nafcillin-d5 (sodium) is the deuterium labeled Nafcillin sodium. Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections[1][2].
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Nafcillin-d5 sodium | 97.74% | Nafcillin-d5 (sodium) is the deuterium labeled Nafcillin sodium. Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections. | ||||||||||||||||||||
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Nafcillin sodium | Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections. | |||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Tan AK, et, al. Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase. Biochem J. 1992 Jan 1;281 ( Pt 1)(Pt 1):191-6. [Content Brief]
Keywords
