1357920-84-3
1357920-84-3
Chemical Structure
Belizatinib
Synonym(s): TSR-011
- CAS No.: 1357920-84-3
- Formula:C33H44FN5O3
- Molecular Weight:577.73
IUPAC Name: 4-fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-((1s,4s)-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide
InChIKey: WSTUJEXAPHIEIM-FEGDYQJNSA-N
SMILES: O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
Biological Activity: Belizatinib (TSR-011) is an orally active, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Belizatinib | 99.62% | Belizatinib (TSR-011) is an orally active, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase. | ||||||||||||||||||||
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Keywords
