135991-95-6
Chemical Structure
Tetrindole hydrochloride
- CAS No.: 135991-95-6
- Formula:C20H27ClN2
- Molecular Weight:330.89
IUPAC Name: 8-cyclohexyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole hydrochloride
InChIKey: NDSGWNVNYIVEKU-UHFFFAOYSA-N
SMILES: C12=C(C3=C4N2CCNC4CCC3)C=C(C5CCCCC5)C=C1.Cl
Biological Activity: Tetrindole hydrochloride is a selective inhibitor of monoamine oxidase A (MAO A). Tetrindole hydrochloride inhibits rat brain mitochondrial MAO A in a competitive manner with a Ki value of 0.4 μM and inhibits MAO B with a Ki of 110 μM. Tetrindole hydrochloride has antidepressant activity[1][2].
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Tetrindole hydrochloride | Tetrindole hydrochloride is a selective inhibitor of monoamine oxidase A (MAO A). Tetrindole hydrochloride inhibits rat brain mitochondrial MAO A in a competitive manner with a Ki value of 0.4 μM and inhibits MAO B with a Ki of 110 μM. Tetrindole hydrochloride has antidepressant activity. | |||||||||||||||||||||
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Keywords