Tetrindole hydrochloride
Based on 1 publication(s) in Google Scholar
Tetrindole hydrochloride is a selective inhibitor of monoamine oxidase A (MAO A). Tetrindole hydrochloride inhibits rat brain mitochondrial MAO A in a competitive manner with a Ki value of 0.4 μM and inhibits MAO B with a Ki of 110 μM. Tetrindole hydrochloride has antidepressant activity.
For research use only. We do not sell to patients.
- CAS No.: 135991-95-6
- Formula: C20H27ClN2
- Molecular Weight:330.89
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Tetrindole hydrochloride
More
Biological Activity
Description
|
MAO-A |
In Vitro
Tetrindole hydrochloride has IC50s of 0.51-1.37 μM for 6 human breast tumor cell lines (MCF-7, HCC1954, T47D, MDA-MB-157, ZR75-1, BT474)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 135991-95-6
-
Molecular Weight 330.89
-
Formula C20H27ClN2
-
SMILES
C12=C(C3=C4N2CCNC4CCC3)C=C(C5CCCCC5)C=C1.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
-
Journal Impact Factor
-
Most Recent
Purity & Documentation
References
[1]. A E Medvedev, et al. Monoamine oxidase inhibition by novel antidepressant tetrindole. Biochem Pharmacol. 1994 Jan 20;47(2):303-8. [Content Brief]
[2]. William D Gwynne, et al. Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells. Cell Mol Biol Lett. 2019 Nov 12;24:59. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tetrindole hydrochloride Related Classifications
HY-101169A Related Classifications
Powered by Bioz