2. Neuronal Signaling
  3. Monoamine Oxidase
  4. Tetrindole hydrochloride

Tetrindole hydrochloride is a selective inhibitor of monoamine oxidase A (MAO A). Tetrindole hydrochloride inhibits rat brain mitochondrial MAO A in a competitive manner with a Ki value of 0.4 μM and inhibits MAO B with a Ki of 110 μM. Tetrindole hydrochloride has antidepressant activity.

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Tetrindole hydrochloride

Tetrindole hydrochloride Chemical Structure

CAS No. : 135991-95-6

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Tetrindole hydrochloride Related Antibodies

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Description

Tetrindole hydrochloride is a selective inhibitor of monoamine oxidase A (MAO A). Tetrindole hydrochloride inhibits rat brain mitochondrial MAO A in a competitive manner with a Ki value of 0.4 μM and inhibits MAO B with a Ki of 110 μM. Tetrindole hydrochloride has antidepressant activity[1][2].

IC50 & Target[1][2]

MAO-A

 

Molecular Weight

330.89

Formula

C20H27ClN2
CAS No.
SMILES

C12=C(C3=C4N2CCNC4CCC3)C=C(C5CCCCC5)C=C1.Cl
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Purity & Documentation
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Tetrindole hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrindole135991-95-6Monoamine OxidaseMAOMAO AmitochondrialMAO BantidepressantInhibitorinhibitorinhibit

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