1361413-10-6
Chemical Structure
RORγt inhibitor 3
- CAS No.: 1361413-10-6
- Formula:C26H20Cl2N2O4S2
- Molecular Weight:559.48
IUPAC Name: N-(5-(2-chlorobenzoyl)-4-(3-chlorophenyl)thiazol-2-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide
InChIKey: GRWNPFJXINLSNF-UHFFFAOYSA-N
SMILES: O=C(C1=C(Cl)C=CC=C1)C2=C(C3=CC(Cl)=CC=C3)N=C(NC(CC4=CC=C(S(=O)(CC)=O)C=C4)=O)S2
Biological Activity: RORγt inhibitor 3 is an orally active and potent retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor. RORγt inhibitor 3 shows high binding affinity and inhibitory activity of Th17 cell differentiation. RORγt inhibitor 3 also shows efficacy in both mouse experimental autoimmune encephalomyelitis (EAE) and collagen induced arthritis (CIA) models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
RORγt inhibitor 3 | RORγt inhibitor 3 is an orally active and potent retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor. RORγt inhibitor 3 shows high binding affinity and inhibitory activity of Th17 cell differentiation. RORγt inhibitor 3 also shows efficacy in both mouse experimental autoimmune encephalomyelitis (EAE) and collagen induced arthritis (CIA) models. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
