1364914-62-4

E67-2 Chemical Structure
1364914-62-4

Chemical Structure

E67-2

  • CAS No.: 1364914-62-4
  • Formula:C21H36N6O2
  • Molecular Weight:404.55

IUPAC Name: 7-((5-aminopentyl)oxy)-N2-(3-(dimethylamino)propyl)-6-methoxy-N4,N4-dimethylquinazoline-2,4-diamine

InChIKey: WLFIYSGBVULZIU-UHFFFAOYSA-N

SMILES: CN(C)C1=C2C=C(OC)C(OCCCCCN)=CC2=NC(NCCCN(C)C)=N1

Biological Activity: E67-2, as the E67 derivative, is a low-toxicity, selective KIAA1718 Jumonji domain inhibitor with an IC50 value of 3.4 µM. E67-2 selectively inhibits histone H3 lysine 9 (H3K9) Jumonji demethylase as well as histone H3 lysine 4 (H3K4) demethylase[1].

Cat. No. Product Name Purity Description Pricing
HY-122746 		E67-2 E67-2, as the E67 derivative, is a low-toxicity, selective KIAA1718 Jumonji domain inhibitor with an IC50 value of 3.4 µM. E67-2 selectively inhibits histone H3 lysine 9 (H3K9) Jumonji demethylase as well as histone H3 lysine 4 (H3K4) demethylase.
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