13799-03-6
13799-03-6
Chemical Structure
Protizinic acid
- CAS No.: 13799-03-6
- Formula:C17H17NO3S
- Molecular Weight:315.39
IUPAC Name: 2-(7-methoxy-10-methyl-10H-phenothiazin-2-yl)propanoic acid
InChIKey: VSQMKHNDXWGCDB-UHFFFAOYSA-N
SMILES: CN1C2=C(C=CC(C(C)C(O)=O)=C2)SC3=CC(OC)=CC=C13
Biological Activity: Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM[1][2].
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Protizinic acid | Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM. | |||||||||||||||||||||
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References
- [1]. K Suzuki, et al. Effects of protizinic acid on leukokinin generation and its physiological action. Agents Actions. 1984 Jun;14(5-6):699-706. [Content Brief]
- [2]. H Ohnishi, et al. Effects of protizinic acid on the prostaglandins system and the production of oxygen radicals. Nihon Yakurigaku Zasshi. 1982 Jun;79(6):561-9. [Content Brief]
Keywords
