1380782-27-3
1380782-27-3
Chemical Structure
T2AA
- CAS No.: 1380782-27-3
- Formula:C15H15I2NO3
- Molecular Weight:511.09
IUPAC Name: (S)-4-(4-(2-amino-3-hydroxypropyl)-2,6-diiodophenoxy)phenol
InChIKey: NKOSKXJRVWVXRI-JTQLQIEISA-N
SMILES: IC(C=C(C[C@H](N)CO)C=C1I)=C1OC2=CC=C(O)C=C2
Biological Activity: T2AA is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase[1].
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T2AA | 99.04% | T2AA is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase. | ||||||||||||||||||||
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References
Keywords
