1383995-51-4
Chemical Structure
Graviquinone
- CAS No.: 1383995-51-4
- Formula:C10H10O4
- Molecular Weight:194.18
IUPAC Name: methyl (E)-3-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acrylate
InChIKey: HVMSPHGUKBLNCL-QPJJXVBHSA-N
SMILES: COC(/C=C/C1(C=CC(C=C1)=O)O)=O
Biological Activity: Graviquinone is a Chk1 inhibitor. Graviquinone exhibits potent cytotoxicity against various cancer cell lines. Graviquinone possesses the characteristics of bypassing ABCB1-mediated multidrug resistance, selectively damaging cancer cell DNA, and regulating the DNA damage response. Graviquinone can also enhance cytotoxicity by increasing ROS levels in cancer cells. Graviquinone can be used for cancer research[1].
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Graviquinone | Graviquinone is a Chk1 inhibitor. Graviquinone exhibits potent cytotoxicity against various cancer cell lines. Graviquinone possesses the characteristics of bypassing ABCB1-mediated multidrug resistance, selectively damaging cancer cell DNA, and regulating the DNA damage response. Graviquinone can also enhance cytotoxicity by increasing ROS levels in cancer cells. Graviquinone can be used for cancer research. | |||||||||||||||||||||
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Keywords
