1385020-40-5
Chemical Structure
Filanesib hydrochloride
Synonym(s): ARRY-520 hydrochloride
- CAS No.: 1385020-40-5
- Formula:C20H23ClF2N4O2S
- Molecular Weight:456.94
IUPAC Name: (Z)-5-(2-(diethylamino)ethyl)-2-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-3-methyl-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one (S)-2-hydroxysuccinate
InChIKey: CTAIFVHCDONNPS-BDQAORGHSA-N
SMILES: O=C(N1[C@@](C2=CC=CC=C2)(CCCN)SC(C3=CC(F)=CC=C3F)=N1)N(OC)C.[H]Cl
Biological Activity: Filanesib hydrochloride (ARRY-520 hydrochloride) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib hydrochloride induces cell death by apoptosis in vitro. Filanesib hydrochloride has potent anti-proliferative activity[1].
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Filanesib hydrochloride | 99.99% | Filanesib hydrochloride (ARRY-520 hydrochloride) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib hydrochloride induces cell death by apoptosis in vitro. Filanesib hydrochloride has potent anti-proliferative activity. | ||||||||||||||||||||
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