1393466-87-9

Plixorafenib Chemical Structure
1393466-87-9

Chemical Structure

Plixorafenib

Synonym(s): PLX8394; FORE8394

  • CAS No.: 1393466-87-9
  • Formula:C25H21F3N6O3S
  • Molecular Weight:542.53

IUPAC Name: (R)-N-(3-(5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide

InChIKey: YYACLQUDUDXAPA-MRXNPFEDSA-N

SMILES: O=C(C1=C(F)C(NS(=O)(N2CC[C@@H](F)C2)=O)=CC=C1F)C3=CNC4=C3C=C(C=N4)C5=CN=C(C6CC6)N=C5

Biological Activity: PLX8394 is a potent and selective BRaf inhibitor, with an IC50 of appr 5 nM for BRAFV600E.

Cat. No. Product Name Purity Description Pricing
HY-18972 		Plixorafenib 99.10% PLX8394 is a potent and selective BRaf inhibitor, with an IC50 of appr 5 nM for BRAFV600E.
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