1395553-31-7
Chemical Structure
AS-1669058 free base
- CAS No.: 1395553-31-7
- Formula:C18H15BrF2N4O
- Molecular Weight:421.24
IUPAC Name: 3-(2-((2-(4-bromo-2,5-difluorophenyl)-6-methylpyrimidin-4-yl)amino)ethyl)pyridine 1-oxide
InChIKey: CCHGKGFZEORIJY-UHFFFAOYSA-N
SMILES: [O-][N+]1=CC=CC(CCNC2=NC(C3=CC(F)=C(Br)C=C3F)=NC(C)=C2)=C1
Biological Activity: AS-1669058 free base is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 free base induces insulin secretion induced by high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 free base improved glucose tolerance and reduced blood glucose levels in db/db mice.
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AS-1669058 free base | AS-1669058 free base is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 free base induces insulin secretion induced by high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 free base improved glucose tolerance and reduced blood glucose levels in db/db mice. | |||||||||||||||||||||
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Keywords
