1404463-20-2
Chemical Structure
2'-F-2'-ara-N2-ibu-dG Phosphoramidite
- CAS No.: 1404463-20-2
- Formula:C45H54FN6O8P
- Molecular Weight:856.92
IUPAC Name: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) (2,4-dimethylpentan-3-yl)phosphonite
InChIKey: AWSRDGSLZILNOE-KVOXTBTPSA-N
SMILES: O=C1NC(NC(C(C)C)=O)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(OCCC#N)C(C(C)C)C(C)C)[C@@H]3F
Biological Activity: 2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
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2'-F-2'-ara-N2-ibu-dG Phosphoramidite | 2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7). | |||||||||||||||||||||
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