1413440-36-4
1413440-36-4
Chemical Structure
AZ-TAK1
- CAS No.: 1413440-36-4
- Formula:C25H28FN7O2
- Molecular Weight:477.53
IUPAC Name: 1-(2-(3-ethyl-5-((5-fluoro-4-(imidazo[1,2-b]pyridazin-3-yl)pyrimidin-2-yl)amino)phenoxy)ethyl)piperidin-4-ol
InChIKey: VZWXALUQDOYOJQ-UHFFFAOYSA-N
SMILES: FC1=C(C2=CN=C3C=CC=NN32)N=C(NC4=CC(OCCN5CCC(CC5)O)=CC(CC)=C4)N=C1
Biological Activity: AZ-TAK1, an ATP-competitive small molecule inhibitor of TAK1, dephosphorylates TAK1, p38, and IκB-α in lymphoma cell lines[1].
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AZ-TAK1 | AZ-TAK1, an ATP-competitive small molecule inhibitor of TAK1, dephosphorylates TAK1, p38, and IκB-α in lymphoma cell lines. | |||||||||||||||||||||
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References
Keywords
