1426960-33-9
1426960-33-9
Chemical Structure
MK-8876
- CAS No.: 1426960-33-9
- Formula:C32H24F2N4O5S
- Molecular Weight:614.62
IUPAC Name: 5-(11-fluoro-6H-pyrido[2',3':5,6][1,3]oxazino[3,4-a]indol-2-yl)-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide
InChIKey: GOHCXBUFLQKEIO-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(C)S(=O)(C)=O)=C(C4=CC=C5C(C(N6CO5)=CC7=C6C=CC=C7F)=N4)C=C13)NC
Biological Activity: MK-8876 is an inhibitor of HCV NS5b site D, which can be used in the research of hepatitis C virus [1][2].
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MK-8876 | MK-8876 is an inhibitor of HCV NS5b site D, which can be used in the research of hepatitis C virus . | |||||||||||||||||||||
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References
- [1]. McLaughlin M, Dermenjian R K, Jin Y, et al. Evaluation and control of mutagenic impurities in a development compound: purge factor estimates vs measured amounts[J]. Organic Process Research & Development, 2015, 19(11): 1531-1535.
- [2]. Williams M J, et al. Process Development of the HCV NS5B Site D Inhibitor MK-8876[J]. Organic Process Research & Development, 2016, 20(7): 1227-1238.
Keywords
