1428126-74-2
1428126-74-2
Chemical Structure
2-Aminopurine dihydrochloride
- CAS No.: 1428126-74-2
- Formula:C5H7Cl2N5
- Molecular Weight:208.05
IUPAC Name: 7H-purin-2-amine dihydrochloride
InChIKey: ZMYNIVFDDGHSJU-UHFFFAOYSA-N
SMILES: NC1=NC2=C(C=N1)NC=N2.Cl.Cl
Biological Activity: 2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence[1][2].
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2-Aminopurine dihydrochloride | 2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence. | |||||||||||||||||||||
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References
- [1]. Jean JM, et al. 2-Aminopurine fluorescence quenching and lifetimes: role of base stacking. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):37-41. [Content Brief]
- [2]. Rachofsky EL, et al. Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence. Biochemistry. 2001 Jan 30;40(4):946-56. [Content Brief]
Keywords
