1430095-30-9
1430095-30-9
Chemical Structure
JAK3-IN-9
- CAS No.: 1430095-30-9
- Formula:C17H23N5O4S
- Molecular Weight:393.46
IUPAC Name: (R)-4-((5-carbamoyl-4-((3-methylbutan-2-yl)amino)pyrimidin-2-yl)amino)phenyl methanesulfonate
InChIKey: PPLPVIMTEDXJNJ-LLVKDONJSA-N
SMILES: CC(C)[C@@H](C)NC1=C(C(N)=O)C=NC(NC2=CC=C(OS(=O)(C)=O)C=C2)=N1
Biological Activity: JAK3-IN-9 is an orally active JAK3 inhibitor with IC50 value of 1.7 nM. JAK3-IN-9 is highly selective to the JAK3 signal path. JAK3-IN-9 is lowly toxic with high oral bioavailability, shows good anti-arthritis activity. JAK3-IN-9 can be used in autoimmune disease research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
JAK3-IN-9 | JAK3-IN-9 is an orally active JAK3 inhibitor with IC50 value of 1.7 nM. JAK3-IN-9 is highly selective to the JAK3 signal path. JAK3-IN-9 is lowly toxic with high oral bioavailability, shows good anti-arthritis activity. JAK3-IN-9 can be used in autoimmune disease research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
