1433-11-0
Chemical Structure
Urea-d4
Synonym(s): Carbonyl diamide-d4
- CAS No.: 1433-11-0
- Formula:CD4N2O
- Molecular Weight:64.08
IUPAC Name: N-(3-(tert-butyl)-5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)phenyl)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide
InChIKey: XSQUKJJJFZCRTK-JBISRTOLSA-N
SMILES: [2H]N([2H])C(N([2H])[2H])=O
Biological Activity: Urea-d4 is the deuterium labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[2]. A potent emollient and keratolytic agent[3]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[4]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
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Urea-d4 | 99.04% | Urea-d4 is the deuterium labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. | ||||||||||||||||||||
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Urea (Standard) | 99.87% | Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. | ||||||||||||||||||||
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Urea-13C,15N2 | 99.95% | Urea-13C,15N2 is the 13C and 15N labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. | ||||||||||||||||||||
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Urea-13C | 99.60% | Urea-13C is the 13C labelled urea. The Urea-13C breath test (13C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection. | ||||||||||||||||||||
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Urea-15N2 | 99.80% | Urea-15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. | ||||||||||||||||||||
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Urea | 99.84% | Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7. [Content Brief]
- [3]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 1519(11):20392.Wang H, et al. Urea. Subcell Biochem. 201473:7-29. [Content Brief]
- [4]. Wang H, et al. Urea. Subcell Biochem. 201473:7-29. [Content Brief]
