1447917-39-6
Chemical Structure
PknB-IN-1
- CAS No.: 1447917-39-6
- Formula:C25H30N2O2
- Molecular Weight:390.52
IUPAC Name: (E)-3-(1-(3-(butyl(methyl)amino)-2-hydroxypropyl)-1H-indol-3-yl)-1-phenylprop-2-en-1-one
InChIKey: GWEHFYMAEAZCBW-CCEZHUSRSA-N
SMILES: CCCCN(CC(CN1C=C(C2=C1C=CC=C2)/C=C/C(C3=CC=CC=C3)=O)O)C
Biological Activity: PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL)[1].
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PknB-IN-1 | PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL). | |||||||||||||||||||||
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Keywords