1449277-10-4

GNE-495 Chemical Structure
1449277-10-4

Chemical Structure

GNE-495

  • CAS No.: 1449277-10-4
  • Formula:C22H20FN5O2
  • Molecular Weight:405.42

IUPAC Name: 8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

InChIKey: FYXCIBJXJYBWPX-UHFFFAOYSA-N

SMILES: O=C(C1=C2C=CC(C3=CC=CC(F)=C3)=NC2=C(N)N=C1)NC4CN(C(C5CC5)=O)C4

Biological Activity: GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.

Cat. No. Product Name Purity Description Pricing
HY-100343
GNE-495 99.49% GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
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HY-100343R
GNE-495 (Standard) ≥98% GNE-495 (Standard) is the analytical standard of GNE-495 (HY-100343). This product is intended for research and analytical applications. GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
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