1451993-12-6
1451993-12-6
Chemical Structure
VU0476406
- CAS No.: 1451993-12-6
- Formula:C21H18FN5OS
- Molecular Weight:407.46
InChIKey: BPGQEZBPFDQHIA-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(C4=CC=CN=C4F)C=C3
Biological Activity: VU0476406 is a blood-brain barrier-permeable and selective muscarinic acetylcholine receptor subtype 4 (M4) activator with human EC50 of 91.0 nM and human pEC50 of 7.04. VU0476406 potentiates endogenous acetylcholine activity at M4 receptors. VU0476406 can be used for the research of Parkinson's disease[1].
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VU0476406 | VU0476406 is a blood-brain barrier-permeable and selective muscarinic acetylcholine receptor subtype 4 (M4) activator with human EC50 of 91.0 nM and human pEC50 of 7.04. VU0476406 potentiates endogenous acetylcholine activity at M4 receptors. VU0476406 can be used for the research of Parkinson's disease. | |||||||||||||||||||||
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References
Keywords
