148-83-4
Chemical Structure
Ostruthin
Synonym(s): Ostruthine
- CAS No.: 148-83-4
- Formula:C19H22O3
- Molecular Weight:298.38
IUPAC Name: 6-acetyl-2-(3,5-dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione
InChIKey: INBMTJJPUABOQJ-VGOFMYFVSA-N
SMILES: C/C(C)=C\CC/C(C)=C/CC1=C(O)C=C2C(C=CC(O2)=O)=C1
Biological Activity: Ostruthin is a natural coumarin compound with bacterial and antimycobacterial activities. Ostruthin inhibits the growth of mycobacteria and Staphylococcus aureus. Ostruthin suppresses vascular smooth muscle cell proliferation as well as de novo cellular DNA synthesis. Ostruthin is applicable to research related to mycobacterial infections and cardiovascular and cerebrovascular diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ostruthin | 98.84% | Ostruthin is a natural coumarin compound with bacterial and antimycobacterial activities. Ostruthin inhibits the growth of mycobacteria and Staphylococcus aureus. Ostruthin suppresses vascular smooth muscle cell proliferation as well as de novo cellular DNA synthesis. Ostruthin is applicable to research related to mycobacterial infections and cardiovascular and cerebrovascular diseases. | ||||||||||||||||||||
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- [1]. Schinkovitz A, et al. Ostruthin: an antimycobacterial coumarin from the roots of Peucedanum ostruthium. Planta Med. 2003;69(4):369-371. [Content Brief]
- [2]. V. DADÁK, et al. Neutralization of the Antibacterial Effect of Natural Coumarin Ostruthine by Vitamins K. Nature volume 205, pages709–710 (1965).
- [3]. Joa H, et al. Identification of ostruthin from Peucedanum ostruthium rhizomes as an inhibitor of vascular smooth muscle cell proliferation. J Nat Prod. 2011;74(6):1513-1516. [Content Brief]
Keywords
