149838-21-1
149838-21-1
Chemical Structure
PD-85639
- CAS No.: 149838-21-1
- Formula:C24H32N2O
- Molecular Weight:364.52
IUPAC Name: N-(3-(2,6-dimethylpiperidin-1-yl)propyl)-2,2-diphenylacetamide
InChIKey: BPZBEIHSHWNWTE-UHFFFAOYSA-N
SMILES: O=C(NCCCN1C(C)CCCC1C)C(C2=CC=CC=C2)C3=CC=CC=C3
Biological Activity: PD-85639 is a voltage-gated sodium (Na+) channel blocker that has neuroprotective effects[1][2].
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PD-85639 | PD-85639 is a voltage-gated sodium (Na+) channel blocker that has neuroprotective effects. | |||||||||||||||||||||
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References
- [1]. A V Shindikar, et al. Design, synthesis and in vivo anticonvulsant screening in mice of novel phenylacetamides. Eur J Med Chem. 2006 Jun;41(6):786-92. [Content Brief]
- [2]. Ioannis Roufos, et al. A Structure-Activity Relationship Study of Novel Phenylacetamides Which Are Sodium Channel Blockers. J. Med. Chem. 1996, 39, 1514-1520.
Keywords
