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Art. -Nr.: HY-135628

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PD-85639

PD-85639 is a voltage-gated sodium (Na+) channel blocker that has neuroprotective effects.

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CAS. Nr.: 149838-21-1
Formel: C₂₄H₃₂N₂O
Molecular Weight:364.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PD-85639 Chemical Structure

CAS. Nr.: 149838-21-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PD-85639 is a voltage-gated sodium (Na+) channel blocker that has neuroprotective effects^[1]^[2].

Alle Sodium Channel Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	2.7 μM Compound: 1	Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cells Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cells	[PMID: 8691482]

Chemical Information

CAS. Nr. 149838-21-1
Molecular Weight 364.52
Formel C₂₄H₃₂N₂O
SMILES

O=C(NCCCN1C(C)CCCC1C)C(C2=CC=CC=C2)C3=CC=CC=C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. A V Shindikar, et al. Design, synthesis and in vivo anticonvulsant screening in mice of novel phenylacetamides. Eur J Med Chem. 2006 Jun;41(6):786-92. [Content Brief]

[2]. Ioannis Roufos, et al. A Structure-Activity Relationship Study of Novel Phenylacetamides Which Are Sodium Channel Blockers. J. Med. Chem. 1996, 39, 1514-1520.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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