149950-61-8
149950-61-8
Chemical Structure
GCA-186
- CAS No.: 149950-61-8
- Formula:C19H26N2O3
- Molecular Weight:330.42
IUPAC Name: 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-isopropylpyrimidine-2,4(1H,3H)-dione
InChIKey: NVGVZWUORYLPAL-UHFFFAOYSA-N
SMILES: O=C1NC(C(C(C)C)=C(N1COCC)CC2=CC(C)=CC(C)=C2)=O
Biological Activity: GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1, 180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively[1].
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GCA-186 | GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1, 180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively. | |||||||||||||||||||||
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References
Keywords
