151808-74-1
Chemical Structure
TP53 neoepitope
- CAS No.: 151808-74-1
- Formula:C45H74N16O13S2
- Molecular Weight:1111.30
InChIKey: JKHMGGRDKLNSFH-PCEWRQEZSA-N
SMILES: O=C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CNC=N2)N
Biological Activity: TP53 neoepitope is a high-affinity antigenic peptide targeting HLA-A. TP53 neoepitope can triggers CD8+ T cell-mediated killing of TP53-mutant tumor cells. TP53 neoepitope is promising for research of solid tumors harboring TP53 hotspot mutations (e.g., R175H, R273H) [1].
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TP53 neoepitope | TP53 neoepitope is a high-affinity antigenic peptide targeting HLA-A. TP53 neoepitope can triggers CD8+ T cell-mediated killing of TP53-mutant tumor cells. TP53 neoepitope is promising for research of solid tumors harboring TP53 hotspot mutations (e.g., R175H, R273H) . | |||||||||||||||||||||
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Keywords
