151937-76-7
Chemical Structure
Penehyclidine hydrochloride
Synonym(s): Penequinine hydrochloride
- CAS No.: 151937-76-7
- Formula:C20H30ClNO2
- Molecular Weight:351.91
IUPAC Name: 1-cyclopentyl-1-phenyl-2-(quinuclidin-3-yloxy)ethan-1-ol hydrochloride
InChIKey: DDTVVMRZNVIVQM-UHFFFAOYSA-N
SMILES: OC(C1CCCC1)(COC2CN3CCC2CC3)C4=CC=CC=C4.[H]Cl
Biological Activity: Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1].
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Penehyclidine hydrochloride | 99.2% | Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation. | ||||||||||||||||||||
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Keywords
