2. GPCR/G Protein Neuronal Signaling NF-κB
  3. mAChR NF-κB
  4. Penehyclidine hydrochloride

Penehyclidine hydrochloride  (Synonyms: Penequinine hydrochloride)

Cat. No.: HY-137976
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Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation.

For research use only. We do not sell to patients.

Penehyclidine hydrochloride Chemical Structure

Penehyclidine hydrochloride Chemical Structure

CAS No. : 151937-76-7

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Penehyclidine hydrochloride Related Antibodies

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Description

Penehyclidine (Penequinine) hydrochloride, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1].

IC50 & Target[1]

mAChR1

 

mAChR3

 

NF-κB

 

Clinical Trial
Molecular Weight

351.91

Formula

C20H30ClNO2
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC(C1CCCC1)(COC2CN3CCC2CC3)C4=CC=CC=C4.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Penehyclidine hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Penehyclidine151937-76-7PenequininemAChRNF-κBMuscarinic acetylcholine receptorNuclear factor-κBNuclear factor-kappaBAnticholinergicM1M3NF-kβpulmonary inflammatorychronic obstructive pulmonary diseaseCOPDInhibitorinhibitorinhibit

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