1523437-16-2
1523437-16-2
Chemical Structure
ML291
- CAS No.: 1523437-16-2
- Formula:C16H16ClN3O6S
- Molecular Weight:413.83
IUPAC Name: N-(4-((4-chloropiperidin-1-yl)sulfonyl)phenyl)-5-nitrofuran-2-carboxamide
InChIKey: XKMLYHZJKCRLOI-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(S(=O)(N3CCC(Cl)CC3)=O)C=C2
Biological Activity: ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ML291 | 99.80% | ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden. | ||||||||||||||||||||
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ML291 (Standard) | ≥98% | ML291 (Standard) is the analytical standard of ML291 (HY-101991). This product is intended for research and analytical applications. ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden. | ||||||||||||||||||||
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References
Keywords
