1. Cell Cycle/DNA Damage
    Apoptosis
  2. PERK
    Eukaryotic Initiation Factor (eIF)
    Apoptosis
  3. ML291

ML291 

Cat. No.: HY-101991
Handling Instructions

ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden.

For research use only. We do not sell to patients.

ML291 Chemical Structure

ML291 Chemical Structure

CAS No. : 1523437-16-2

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Description

ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden[1].

Molecular Weight

413.83

Formula

C16H16ClN3O6S

CAS No.
SMILES

O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(S(=O)(N3CCC(Cl)CC3)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ML291
Cat. No.:
HY-101991
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