1534358-79-6

COH000 Chemical Structure
1534358-79-6

Chemical Structure

COH000

  • CAS No.: 1534358-79-6
  • Formula:C25H25NO5
  • Molecular Weight:419.47

IUPAC Name: dimethyl (1R,4S)-1-((R)-1-(phenylamino)-2-(p-tolyl)ethyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

InChIKey: UFPINDDCTUCUSA-DFIYOIEZSA-N

SMILES: CC(C=C1)=CC=C1C[C@@H](NC2=CC=CC=C2)[C@]34C(C(OC)=O)=C(C(OC)=O)[C@@H](O4)C=C3

Biological Activity: COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro[1].

Cat. No. Product Name Purity Description Pricing
HY-114304 		COH000 98.0% COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro.
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