154086-90-5
154086-90-5
Chemical Structure
9-OAHSA
- CAS No.: 154086-90-5
- Formula:C36H68O4
- Molecular Weight:564.92
IUPAC Name: 9-(oleoyloxy)octadecanoic acid
InChIKey: PGKKGBQMNNEIHV-PFONDFGASA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(OC(CCCCCCCC(O)=O)CCCCCCCCC)=O
Biological Activity: 9-OAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 9-OAHSA shows anti-inflammatory effects via inhibiting cytokine production and reduces IL-1β and IL-6 expression. 9-OAHSA is also a protective molecule to prevent colon carcinoma cells from apoptotic cell death[1][2][3].
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9-OAHSA | 9-OAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 9-OAHSA shows anti-inflammatory effects via inhibiting cytokine production and reduces IL-1β and IL-6 expression. 9-OAHSA is also a protective molecule to prevent colon carcinoma cells from apoptotic cell death. | |||||||||||||||||||||
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References
- [1]. Zhu QF, et al. Highly sensitive determination of fatty acid esters of hydroxyl fatty acids by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:34-40.2. [Content Brief]
- [2]. Ding J, et al. In-Silico-Generated Library for Sensitive Detection of 2-Dimethylaminoethylamine Derivatized FAHFA Lipids Using High-Resolution Tandem Mass Spectrometry. Anal Chem. 2020 Apr 21;92(8):5960-5968. [Content Brief]
- [3]. Li L, et al. Fatty acid esters of hydroxy fatty acids: A potential treatment for obesity-related diseases. Obes Rev. 2024 Mar 10:e13735. [Content Brief]
Keywords
