155326-57-1
155326-57-1
Chemical Structure
15-Keto Iloprost
- CAS No.: 155326-57-1
- Formula:C22H30O4
- Molecular Weight:358.47
InChIKey: LDICATDQJSBQOX-JNSFOOLWSA-N
SMILES: O[C@@H]1C[C@@]2([H])[C@]([C@H]1/C=C/C(C(CC#CC)C)=O)([H])C/C(C2)=C/CCCC(O)=O
Biological Activity: 15-Keto Iloprost is a C-15 oxidized derivative of Iloprost (HY-A0096). Iloprost (ZK 36374) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis[1][2].
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15-Keto Iloprost | 15-Keto Iloprost is a C-15 oxidized derivative of Iloprost (HY-A0096). Iloprost (ZK 36374) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. | |||||||||||||||||||||
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References
- [1]. Schrör K, et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK 36 374)--equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol. 1981 Jun;316(3):252-5. [Content Brief]
- [2]. Kowalczyk-Zieba I, et al. Iloprost affects in vitro maturation and developmental competence of bovine oocytes. Theriogenology. 2020 Nov;157:286-296. [Content Brief]
Keywords
