1595278-21-9
1595278-21-9
Chemical Structure
GSK717
- CAS No.: 1595278-21-9
- Formula:C28H28N4O2
- Molecular Weight:452.55
IUPAC Name: N-(2-(1-(2-((2,3-dihydro-1H-inden-5-yl)amino)-2-oxoethyl)-1H-benzo[d]imidazol-2-yl)ethyl)-N-methylbenzamide
InChIKey: YDOATJUIIFWTKQ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C2C(CCC2)=C1)CN3C4=CC=CC=C4N=C3CCN(C)C(C5=CC=CC=C5)=O
Biological Activity: GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK717 | 99.93% | GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells. | ||||||||||||||||||||
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References
Keywords
