1605304-31-1
Chemical Structure
VUF14480
- CAS No.: 1605304-31-1
- Formula:C17H20N4
- Molecular Weight:280.38
IUPAC Name: 4-(4-methylpiperazin-1-yl)-6-phenyl-2-vinylpyrimidine
InChIKey: IQEYEGMWJXOFAC-UHFFFAOYSA-N
SMILES: N=1C(=NC(=CC1C=2C=CC=CC2)N3CCN(C)CC3)C=C
Biological Activity: VUF14480 is a partial agonist of histamine H4 (hH4) receptor-mediated G protein signalling and β-arrestin2 recruitment. VUF14480 binds covalently to hH4 receptor (pKi: 6.3 for hH4-WT receptor). VUF14480 partially induces hH4 receptor-mediated G protein activation and β-arrestin2 recruitment. VUF14480 can be used in the research of inflammatory diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
VUF14480 | VUF14480 is a partial agonist of histamine H4 (hH4) receptor-mediated G protein signalling and β-arrestin2 recruitment. VUF14480 binds covalently to hH4 receptor (pKi: 6.3 for hH4-WT receptor). VUF14480 partially induces hH4 receptor-mediated G protein activation and β-arrestin2 recruitment. VUF14480 can be used in the research of inflammatory diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
