1607824-64-5
1607824-64-5
Chemical Structure
Naratuximab emtansine
Synonym(s): IMGN529; Debio 1562
- CAS No.: 1607824-64-5
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Naratuximab emtansine]
Biological Activity: Naratuximab emtansine (IMGN529) is a CD37-targeted ADC consisting of a humanized IgG1 mAb coupled to the microtubule disruptor DM1. Naratuximab emtansine has high affinity and specificity for CD37, allowing ADC internalization, processing and intracellular release of DM1. Due to its ability to disrupt microtubule assembly, DM1 can subsequently induce cell cycle arrest and apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naratuximab emtansine | 98.52% | Naratuximab emtansine (IMGN529) is a CD37-targeted ADC consisting of a humanized IgG1 mAb coupled to the microtubule disruptor DM1. Naratuximab emtansine has high affinity and specificity for CD37, allowing ADC internalization, processing and intracellular release of DM1. Due to its ability to disrupt microtubule assembly, DM1 can subsequently induce cell cycle arrest and apoptosis. | ||||||||||||||||||||
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Keywords
