1614229-04-7
Chemical Structure
Trk-IN-2
- CAS No.: 1614229-04-7
- Formula:C24H24N10O
- Molecular Weight:468.53
IUPAC Name: 2-(4-(6-(1H-imidazol-1-yl)pyridin-3-yl)-1H-1,2,3-triazol-1-yl)-N-(3-(tert-butyl)-1-(pyridin-3-yl)-1H-pyrazol-5-yl)acetamide
InChIKey: ZKPYYDAYCYGVLR-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(=NN1C=2C=NC=CC2)C(C)(C)C)CN3N=NC(=C3)C=4C=NC(=CC4)N5C=NC=C5
Biological Activity: Trk-IN-2 is an orally active pan-Trk kinase inhibitor with an TrkA IC50 of 9 nM. Trk-IN-2 exhibits pharmacodynamic effects in rat models of inflammatory pain and neuropathic pain.Trk-IN-2 can be used for the research of inflammatory pain, neuropathic pain[1].
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Trk-IN-2 | Trk-IN-2 is an orally active pan-Trk kinase inhibitor with an TrkA IC50 of 9 nM. Trk-IN-2 exhibits pharmacodynamic effects in rat models of inflammatory pain and neuropathic pain.Trk-IN-2 can be used for the research of inflammatory pain, neuropathic pain. | |||||||||||||||||||||
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Keywords
