1617518-22-5
1617518-22-5
Chemical Structure
HJC0416
- CAS No.: 1617518-22-5
- Formula:C18H17ClN2O4S
- Molecular Weight:392.86
IUPAC Name: 2-(3-aminopropoxy)-5-chloro-N-(1,1-dioxidobenzo[b]thiophen-6-yl)benzamide
InChIKey: AUTAJMGNRLHARZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=CS2(=O)=O)C2=C1)C3=CC(Cl)=CC=C3OCCCN
Biological Activity: HJC0416 is a potent and orally active STAT3 inhibitor. HJC0416 shows antiprolifeative activity and induces Apoptosis. HJC0416 decreases the expression of p-STAT3 (Tyr-705), Cyclin D1 and increases the expression of cleaved caspase-3 protein. HJC0416 shows anti-tumor activity[1].
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HJC0416 | HJC0416 is a potent and orally active STAT3 inhibitor. HJC0416 shows antiprolifeative activity and induces Apoptosis. HJC0416 decreases the expression of p-STAT3 (Tyr-705), Cyclin D1 and increases the expression of cleaved caspase-3 protein. HJC0416 shows anti-tumor activity. | |||||||||||||||||||||
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References
Keywords
