163163-23-3
163163-23-3
Chemical Structure
Chromanol 293B
- CAS No.: 163163-23-3
- Formula:C15H20N2O4S
- Molecular Weight:324.40
IUPAC Name: N-((3R,4S)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-methylethanesulfonamide
InChIKey: HVSJHHXUORMCGK-UONOGXRCSA-N
SMILES: CCS(N([C@H]1C2=CC(C#N)=CC=C2OC(C)([C@@H]1O)C)C)(=O)=O
Biological Activity: Chromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM[1].
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Chromanol 293B | 99.2% | Chromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM. | ||||||||||||||||||||
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References
Keywords
