163271-32-7
163271-32-7
Chemical Structure
5-ALA benzyl ester hydrochloride
Synonym(s): Benzyl-ALA hydrochloride
- CAS No.: 163271-32-7
- Formula:C12H16ClNO3
- Molecular Weight:257.71
IUPAC Name: benzyl 5-amino-4-oxopentanoate hydrochloride
InChIKey: GHMCTRQKEALPCK-UHFFFAOYSA-N
SMILES: O=C(OCC1=CC=CC=C1)CCC(CN)=O.[H]Cl
Biological Activity: 5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines[1][2].
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5-ALA benzyl ester hydrochloride | 99.08% | 5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines. | ||||||||||||||||||||
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References
- [1]. Hirschberg H, et al. ALA- and ALA-ester-mediated photodynamic therapy of human glioma spheroids. J Neurooncol. 2002 Mar;57(1):1-7. [Content Brief]
- [2]. Brunner H, et al. The effects of 5-aminolevulinic acid esters on protoporphyrin IX production in human adenocarcinoma cell lines. Photochem Photobiol. 2001 Nov;74(5):721-5. [Content Brief]
Keywords
