1639040-91-7
1639040-91-7
Chemical Structure
EGFR-IN-199
- CAS No.: 1639040-91-7
- Formula:C26H20FN5O
- Molecular Weight:437.47
IUPAC Name: N-(4-((1-(3-fluorobenzyl)-1H-indol-5-yl)amino)quinazolin-6-yl)acrylamide
InChIKey: CWFVSHJUGHKLMO-UHFFFAOYSA-N
SMILES: C=CC(NC1=CC2=C(N=CN=C2C=C1)NC3=CC4=C(C=C3)N(C=C4)CC5=CC=CC(F)=C5)=O
Biological Activity: EGFR-IN-199 is a selective and potent EGFR inhibitor with IC50 values of 1.1 nM and 1.4 nM for purified EGFR WT and EGFRT790M/L858R kinases. EGFR-IN-199 can be used for the research of cancer[1].
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EGFR-IN-199 | EGFR-IN-199 is a selective and potent EGFR inhibitor with IC50 values of 1.1 nM and 1.4 nM for purified EGFR WT and EGFRT790M/L858R kinases. EGFR-IN-199 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
