1650569-94-0
Chemical Structure
AmPEG6C2-Aur0131
- CAS No.: 1650569-94-0
- Formula:C54H92N6O15
- Molecular Weight:1065.34
IUPAC Name: ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-1-(1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oyl)-2-methylpyrrolidine-2-carboxamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine
InChIKey: JKVBOSLOHJCKQR-NOWWAFAQSA-N
SMILES: NCCOCCOCCOCCOCCOCCOCCC(N1[C@@](C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@H]([C@H](OC)[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)CCC2)=O)=O)=O)(C)CCC1)=O
Biological Activity: AmPEG6C2-Aur0131 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0131 (an auristatin microtubule inhibitor), linked via the non-cleavable linker AmPEG6C2[1].
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AmPEG6C2-Aur0131 | AmPEG6C2-Aur0131 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0131 (an auristatin microtubule inhibitor), linked via the non-cleavable linker AmPEG6C2. | |||||||||||||||||||||
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Keywords
